阅读理解韦尼克脑病诊治挑战2例报告
NutrClinPract.Apr;31(2):-90.
ChallengesinDiagnosisandTreatmentofWernickeEncephalopathy:Reportof2Cases.
InfanteMT,FancelluR,MurialdoA,BarlettaL,CastellanL,SerratiC.
UniversityofGenoa,LargoP.Daneo,Genoa,Italy.
IRCCSSanMartinoUniversityHospitalIST,LargoR.Benzi,Genoa,Italy.
BACKGROUND:Wernickeencephalopathy(WE)isamedicalemergencycausedbythiaminedeficiency,characterizedbycerebellarataxia,ophthalmoplegia,andcognitivedisturbancesthatmayprogresstoKorsakoffamnesia.Wedescribe2patientswithWEwhoneededhigh-doseandlong-termtreatmentwiththiaminetoobtainneurologicalimprovementandrecovery.
CASEDESCRIPTION:Thefirstpatientwasawomandiagnosedwithnon-Hodgkinlymphoma.Afteragastrointestinalinfection,shedevelopeddepression,memoryloss,disorientation,behavioralchanges,andataxicparaplegia.Brainmagneticresonanceimaging(MRI)showedbilateralalterationsinthalamic,frontal,andperiaqueductalregions,suggestiveofWE.Thesecondpatientwasamanwholost10kgaftersurgicalgastrectomy;hedevelopeddiplopia,ophthalmoplegia,cerebellarataxia,lowerlimbparesthesias,andamnesia.AbrainMRIdemonstratedcontrastenhancementofmammillarybodies,北京看白癜风效果最好医院北京专业白癜风医院
